In the closing days of World War II, family doctor Akagi runs (literally) from patient to patient in a small Japanese seaside village and discovers an alarming increase in hepatitis among his increasingly war-weary patients. He seeks a cure but the government is more interested in preparing for The Final Battle as the war draws inevitably to a close. He enlists the support of a diverse collection of friends including a morphine addicted surgeon, a hedonistic monk, and a young recovering prostitute who inevitably falls in love with him.